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NEW PRODUCT INTRODUCTION: STAX™ MAX PLATFORM

October 11, 2017

The Stax mAx clarification platform is a single-use, robust, depth filtration solution for the economic clarification of monoclonal antibody cell cultures without the need for centrifugation or process additives. The platform is optimized to maintain performance as cell density and viability change to minimize the impact of process variability between batches and to deliver a platform that retains a small footprint across a wide range of feed streams with cell densities of up 35 x 106 cells/mL and feed turbidities of up to 3000 NTU.

 

The platform applies two stages of filtration, each with two layers of pharmaceutical grade depth-filter media with sequentially finer grades to remove aggregates, whole cells and cell debris.  This construction produces a consistent low turbidity effluent with a consistent high throughput even as cell density increases or cell viability decreases.



The same media configurations are available in a number of formats to scale directly from bench-top testing up to large-scale clinical production.

 

The combination of robust performance, scalability and simplicity make the Stax mAx clarification platform the right choice to accelerate process development and to provide high quality filtrate in a low footprint, economic system.

The Stax mAx platform is optimized to maintain performance as cell density and viability change to minimize the impact of process variability between batches and to deliver a platform that retains a small footprint across a wide range of feed streams as it scales from bench-top testing to large scale clinical production.